PRODUCT DESCRIPTION:

Methylene Blue is a multifunctional injectable medication used primarily as an antidote for methemoglobinemia, urinary tract antiseptic, and intraoperative tissue stain.

It plays a critical role in clinical emergencies and surgical diagnostics, particularly in toxicology, critical care, and urology.

This 10 MG/ML pre-filled syringe format offers convenience, accuracy, and reduced preparation time—especially vital in ICU and emergency settings. Sterile and ready-to-use, it ensures precise dosing and patient safety.

Formulation & Presentation:

• Dosage Form: Sterile Injectable
• Presentation: Both in Lyophilized & Pre-Filled Syringe (customizable as per market demand)
• Available Strengths:
  • 10 MG/ ML
• Route of Administration: Intraoperative as directed/ Intravenous (IV) Slow Injection/ Infusion after appropriate reconstitution or as per clinical indication and severity. Reconstituted as per protocol Intravenous infusion. To be administered under supervision of a qualified oncologist or day-care oncology units. (As per physician’s discretion or decision) Administered as continuous infusion, typically as part of combination chemotherapy regimens

Therapeutic Indications:

• Acute methemoglobinemia
• Surgical staining (e.g., sentinel lymph node biopsy)
• Ifosfamide-induced encephalopathy (off-label)
• Urinary tract antisepsis
• Antiseptic irrigation (diluted use under supervision)

Side Effects:

• COMMON:
  • Green or blue discoloration of urine or feces
  • Nausea, dizziness
  • Skin staining at the injection site
• SERIOUS (RARE):
  • Serotonin syndrome (especially with SSRIs)
  • Hemolytic anemia in G6PD-deficient patients
  • Chest tightness, confusion
• PRECAUTIONS:
  • Screen for G6PD deficiency before use
  • Use cautiously in patients on SSRIs, MAO inhibitors
  • Avoid rapid IV push; administer slowly to avoid local irritation
  • Monitor oxygenation and vital signs post-administration
  • Not recommended in pregnancy unless critically indicated